drugset / Trial / NCT03809884

Dietary Counseling or Potassium Supplement to Increase Potassium Intake in Patients With High Blood Pressure

NCT03809884

Phase 3 Completed 7 enrolled Ottawa Hospital Research Institute
Non-randomizedSequentialOpen-labelTreatment

Summary

High blood pressure is the leading cause of cardiovascular disease worldwide. Many medicines are available to lower blood pressures successfully, as well as many non-medical options, such as dietary changes. Some effective dietary changes include decreasing sodium and increasing potassium in the diet. A lot of focus has been on sodium intake yet; potassium intake in the diet remains low amongst adult Canadians. Excellent data exist in the published research reporting that increasing potassium intake, either as diet or even as supplements, reduces blood pressure and reduces risk of cardiovascular outcomes such as stroke. The overall purpose of this study is to reveal the most effective way of increasing potassium, amongst participants with high blood pressure whose existing intake of potassium is low. In the first stage, participants with high blood pressure and proven low potassium intake will receive dietary counselling. If after 4 weeks, there has not been a desired increase in potassium intake, the patients will be prescribed an additional potassium supplement.

Timeline

Start
2019-12-01
Primary completion
2024-07-22
Completion
2024-07-22

Drugs

EvaluationDrugModalityDoseRoute
Comparator POTASSIUM CITRATE ANHYDROUS Small molecule 50 mmol Oral
Comparator POTASSIUM CITRATE ANHYDROUS Small molecule 100 mmol Oral

Indications