drugset / Trial / NCT03818165

Phase 1b Study of CAR2Anti-CEA CAR-T Cell Hepatic Infusions for Pancreatic Carcinoma Patients With CEA+ Liver Metastases

NCT03818165 ↗

Phase 1 Terminated 2 enrolled Sorrento Therapeutics, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This study is an open-label, single arm phase 1b safety study of CAR2 Anti-CEA CAR-T cell hepatic arterial infusions for pancreatic carcinoma patients with carcinoembryonic antigen positive (CEA+) liver metastases resistant to standard therapy who meet all other eligibility criteria.

Timeline

Start
2019-07-29
Primary completion
2020-01-19
Completion
2021-05-21

Outcome

Outcome not reported

Stopped (Enrollment): “Limited enrollment.”

Drugs

EvaluationDrugModalityDoseRoute
Subject CAR2 Anti-CEA CAR-T cells Cell therapy 1e+10 cells Other

Indications