drugset / Trial / NCT03821376

Correlation of Renal Mass Pathologic Grade and Contrast Enhanced Ultrasound (CEUS)

NCT03821376

Phase 4 Terminated 12 enrolled Indiana University
NaSingle-groupOpen-labelDiagnostic

Summary

Patients with renal lesions suspicious for renal cell carcinoma (RCC) have a variety of different treatment pathways available to them. Imaging surveillance is being used frequently on smaller renal masses, and radiologists are being asked to biopsy more renal lesions to better guide decision making by urology. This is in large part due to the pathologic grade of renal masses having been shown to correlate with patient outcomes. The World Health Organization (WHO) or Fuhrman grade is the standard grading scale used by pathologists for RCC. The goal of this study will be to correlate contrast enhanced ultrasound findings with the pathologic grade of RCC. Specifically, the investigators hypothesize that tumors with different pathologic grades will show different patterns of qualitative enhancement, as well as different perfusion kinetics.

Timeline

Start
2019-07-16
Primary completion
2021-09-21
Completion
2021-09-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Lumason Diagnostic / imaging agent 2.5 ml Intravenous

Indications