drugset / Trial / NCT03821701

Effect of Angiotensin-Neprilysin Inhibition (ARNI) on Prognosis of Chronic Heart Failure

NCT03821701

RandomizedParallel-groupOpen-labelTreatment

Summary

This study is a randomized controlled multicenter clinical trial, in which about 340 patients with newly diagnosed or prior diagnosed chronic heart will be recruited. Patients will be randomly divided into Angiotensin-Neprilysin Inhibition (ARNI) group and angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (ACEI/ARB) group. All-cause death, cardiac death and re-hospitalization due to heart failure will be evaluated in 1, 3, 6, 12 months after recruitment.

Timeline

Start
2018-06-01
Primary completion
2021-01-31
Completion
2022-01-31

Drugs

EvaluationDrugModalityDoseRoute
Subject LCZ696 Unknown 100 mg

Indications