Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

Summary

The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.

Timeline

Start

2019-06-27

Primary completion

2030-05

Completion

2030-05

Publications

• Kantarci K, Kapoor E, Geske JR, Castillo A, Fields JA, Kara F, Knyazhanskaya EE, Schwarz CG, Senjem ML, Bailey KR, Lowe V, LeBrasseur NK, Rocca WA, Mielke MM. Premenopausal bilateral oophorectomy and Alzheimer's disease imaging biomarkers later in life. Alzheimers Dement. 2025 Jul;21(7):e14469. doi: 10.1002/alz.14469. Epub 2024 Dec 23.

Drugs

Indications