drugset / Trial / NCT03824678

Evaluate the Pharmacokinetics of CC-220 in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared With Healthy Subjects

NCT03824678

Phase 1 Completed 40 enrolled Celgene Corporation
NaSingle-groupOpen-labelTreatment

Summary

This is a multicenter, open-label study to assess the PK of a single 1-mg oral dose of CC-220 in subjects with mild, moderate, and severe hepatic impairment, and in matched healthy control subjects with normal hepatic function. Degree of hepatic impairment will be determined during the Screening period by the subject's score according to Child-Pugh Classification Criteria

Timeline

Start
2019-02-13
Primary completion
2019-06-18
Completion
2019-06-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Iberdomide Small molecule 1 mg Oral

Indications

No indication recorded.