drugset / Trial / NCT03826992

Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

NCT03826992

Phase 1 Recruiting 21 enrolled Children's Hospital Medical Center, Cincinnati
NaSingle-groupOpen-labelTreatment

Summary

This study evaluates the safety and tolerability of combining venetoclax with Vyxeos (CPX-351) in pediatric and young adult patients with acute leukemia that has come back or not responded to treatment.

Timeline

Start
2018-12-27
Primary completion
2027-01
Completion
2028-01

Drugs

EvaluationDrugModalityDoseRoute
Subject CPX-351 Other / unclassified 44 mg/m2 Intravenous
Subject CPX-351 Other / unclassified 100 mg/m2 Intravenous
Subject Venetoclax Small molecule Oral

Indications