drugset / Trial / NCT03827447

Vancomycin for the Treatment of NAAT(+)/Toxin(-) C. Difficile

NCT03827447

Phase 1 Completed 7 enrolled Medical College of Wisconsin
RandomizedParallel-groupTriple-blindTreatment

Summary

This study proposes to: 1. Characterize the impact of oral vancomycin on C. difficile loads after end of treatment compared to a placebo group. 2. Determine the effect of oral vancomycin on structural and functional microbiome changes after end of treatment compared to a placebo group. 3. Characterize the impact of oral vancomycin against a placebo group on the daily frequency of loose stools by the end of treatment.

Timeline

Start
2019-07-17
Primary completion
2021-06-01
Completion
2021-06-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Vancomycin Other / unclassified 125 mg Oral