drugset / Trial / NCT03836157

Mirvetuximab Soravtansine (IMGN853) and Bevacizumab in Patients With Endometrial Cancer

NCT03836157

NaSingle-groupOpen-labelTreatment

Summary

IMGN853 is designed to inhibit cell division and cell growth of folate receptor 1 (FRα)-expressing tumor cells. The purpose of this study is to test the safety of IMGN853 and bevacizumab and see what effects (good and bad) that this combination treatment has on subjects with recurrent endometrial cancer.

Timeline

Start
2019-05-31
Primary completion
2021-11-30
Completion
2022-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 15 mg/kg Intravenous
Subject Mirvetuximab Soravtansine Other / unclassified 6 mg/kg Intravenous