Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origin

Summary

A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origin

Timeline

Start

2019-01-22

Primary completion

2019-12-10

Completion

2020-01-21

Outcome

Missed primary endpoint

registry analysis (superiority test); Placebo vs Serlopitant 5 mg; p = 0.5861; Treatment Effect -1.4 (95% CI -13.9 to 11.1) NCT03841331 ↗

registry analysis (superiority test); Placebo vs Serlopitant 5 mg; p = 0.2440; Mean Difference (Final Values) 2.44 (95% CI -4.98 to 9.87) NCT03841331 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Serlopitant	Small molecule	5 mg	—

Indications

No indication recorded.