drugset / Trial / NCT03843359
A First Time in Human (FTIH) Study of GSK3745417 Administered to Participants With Advanced Solid Tumors
Non-randomizedSequentialOpen-labelTreatment
Summary
This study aims to evaluate the safety, tolerability, and preliminary clinical activity and establish a recommended dose of GSK3745417 administered alone (Part 1A) or co-administered (Part 2A) with dostarlimab in participants with refractory/relapsed solid tumors. Both parts will consist of a dose escalation phase.
Timeline
- Start
- 2019-03-12
- Primary completion
- 2024-04-04
- Completion
- 2026-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GSK3745417 | Unknown | — | — |
| Background | Dostarlimab | Monoclonal antibody | — | — |