drugset / Trial / NCT03845296

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

NCT03845296

NaSingle-groupOpen-labelTreatment

Summary

This phase II Lung-MAP trial studies how well rucaparib works in treating patients with genomic loss of heterozygosity (LOH) high and/or deleterious BRCA1/2 mutation stage IV non-small cell lung cancer or that has come back. Rucaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2019-04-16
Primary completion
2022-01-01
Completion
2024-09-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Rucaparib Small molecule Oral