drugset / Trial / NCT03845881

Trial Comparing a Multi-Modal Pain Protocol With and Without Opioids Following Total Joint Arthroplasty

NCT03845881

RandomizedSingle-groupDouble-blindTreatment

Summary

To help curb the use of opioid medications following orthopedic surgery investigators have developed a new multi-modal pain pathway. Investigators aim to compare this regimen with and without the inclusion of opioid medications. This study will be performed in a randomized, double-blinded, placebo-controlled fashion in patients undergoing primary total knee or total hip arthroplasty. Investigators hypothesize that the opioid devoid pathway will show equivalent pain scores to the pathway that includes opioids while also having less constipation, nausea, and vomiting following surgery. If successful, this would create a dramatic decrease in opioid consumption following orthopedic surgery while still providing appropriate pain relief to patients.

Timeline

Start
2019-04-10
Primary completion
2020-07-28
Completion
2020-07-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Oxycodone Other / unclassified

Indications

No indication recorded.