drugset

drugset / Trial / NCT03847610

Minimally Invasive Sensing of Beta-lactam Antibiotics

NCT03847610 ↗

Phase 1 Completed 11 enrolled Imperial College London

NaSingle-groupOpen-labelDevice feasibility

Summary

This study is an in-house feasibility study of a microneedle biosensor developed within Imperial College London.

Timeline

Start: 2018-04-12
Primary completion: 2018-08-10
Completion: 2018-08-10

Publications

Rawson TM, Gowers SAN, Freeman DME, Wilson RC, Sharma S, Gilchrist M, MacGowan A, Lovering A, Bayliss M, Kyriakides M, Georgiou P, Cass AEG, O'Hare D, Holmes AH. Microneedle biosensors for real-time, minimally invasive drug monitoring of phenoxymethylpenicillin: a first-in-human evaluation in healthy volunteers. Lancet Digit Health. 2019 Nov;1(7):e335-e343. doi: 10.1016/S2589-7500(19)30131-1. Epub 2019 Sep 30.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Penicillin V	Small molecule	500 mg	Oral

Indications

No indication recorded.