drugset / Trial / NCT03847883
Low-dose Versus Standard Dose Alteplase in Acute Ischemic Stroke , 4 Monthes Prospective Study
Phase 4
Completed
408 enrolled
Department of Medical Services Ministry of Public Health of Thailand
Lumpang Hospital · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
Cohort A Randomized Control trial of Ateplase 0.6, 0.75 and 0.9 mg/kg in 78 patients Cohort B single arm 0.9 mg/kg Ateplase in 330 patients Combined Cohort A and B evaluate different of death, intra-cerebral hemorrhage, numberof patient with mRS 0-1 at discharge and 3 months follow up, and other important stroke outcomes
Timeline
- Start
- 2011-01-01
- Primary completion
- 2018-12-31
- Completion
- 2019-02-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ateplase | Unknown | 0.6 mg/kg | Intravenous |
| Comparator | Ateplase | Unknown | 0.75 mg/kg | Intravenous |
| Comparator | Ateplase | Unknown | 0.9 mg/kg | Intravenous |