CBDV vs Placebo in Children and Adults up to Age 30 With Prader-Willi Syndrome (PWS)

Summary

This study aims to examine the feasibility and safety of cannabidivarin (CBDV) as a treatment for children and young adults with PWS.

Timeline

Start

2020-11-23

Primary completion

2024-10-31

Completion

2024-10-31

Outcome

Outcome not reported

Stopped (Business): “Only limited funding was available and the study was never able to be conducted to its natural conclusion.”

Publications

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• Background Irizarry KA, Miller M, Freemark M, Haqq AM. Prader Willi Syndrome: Genetics, Metabolomics, Hormonal Function, and New Approaches to Therapy. Adv Pediatr. 2016 Aug;63(1):47-77. doi: 10.1016/j.yapd.2016.04.005. No abstract available.
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• Background Rock EM, Sticht MA, Duncan M, Stott C, Parker LA. Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Delta(9) -tetrahydrocannabivarin (THCV), to produce CB1 receptor inverse agonism symptoms of nausea in rats. Br J Pharmacol. 2013 Oct;170(3):671-8. doi: 10.1111/bph.12322.
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Drugs

Indications