Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy

Summary

Randomized clinical trial in the Logo health zone, in Ituri province, Democratic Republic of Congo to compare seizure freedom in onchocerciasis infested epilepsy patients who ivermectin treatment once a year compared to 2 and 3 times a year. All participants also receive anti-epileptic drugs according to local guidelines for epilepsy treatment. Participants will be followed for 12 months. The primary endpoint is seizure freedom defined as no seizures during the last fourth months of the trial.

Timeline

Start

2017-10-01

Primary completion

2019-03-31

Completion

2019-07-01

Drugs

Indications