Effect of Pancreatic Polypeptide on Gastric Motor Function and Food Intake in Humans

Phase 4 Completed 12 enrolled Universitaire Ziekenhuizen KU Leuven

RandomizedCrossoverSingle-blindPrevention

Summary

The investigators want to observe whether different doses of pancreatic polypeptide infusions influence gastric accommodation (measured as intragastric pressure changes during a liquid meal infusion), gastric emptying and food intake.

Timeline

Start: 2010-08-31
Primary completion: 2011-03-08
Completion: 2011-03-08

Publications

Verbeure W, Rotondo A, Janssen P, Carbone F, Tack J. Supraphysiological effects of pancreatic polypeptide on gastric motor function and nutrient tolerance in humans. Physiol Rep. 2021 Sep;9(17):e15002. doi: 10.14814/phy2.15002.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Pancreatic Polypeptide	Peptide	3 unknown	Intravenous
Subject	Pancreatic Polypeptide	Peptide	10 unknown	Intravenous

Indications

No indication recorded.