Safety and Efficacy of Mometasone Furoate Nasal Spray With the Addition of Loratadine Versus Placebo in Participants With Seasonal Allergic Rhinitis (C94-145)

Summary

The purpose of this study is to evaluate the safety and efficacy of mometasone furoate nasal spray (MFNS) with the addition of loratadine vs MFNS alone, loratadine alone, or placebo, in the treatment of patients with seasonal allergic rhinitis.

Timeline

Start

1995-03-01

Primary completion

1995-08-07

Completion

1995-08-07

Outcome

Missed primary endpoint

registry analysis (superiority test); MFNS 200 μg + Loratadine 10 mg vs MFNS 200 μg; p = 0.36; ANOVA NCT03855228 ↗

registry analysis (superiority test); MFNS 200 μg + Loratadine 10 mg vs MFNS 200 μg; p = 0.35; ANOVA NCT03855228 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Loratadine	Small molecule	10 mg	Oral
Subject	Mometasone furoate	Other / unclassified	200 ug	Intranasal

Indications