Oxytocin on Approach Bias and Craving

Summary

This will be a laboratory-based investigation of the behavioral and neural effects of intranasal oxytocin on craving for alcohol and approach bias in moderate to heavy alcohol using subjects. This study uses a within-subject, randomized, placebo-controlled, counterbalanced, crossover design to compare the effects oxytocin and placebo. In this way, all subjects will be scanned twice; once following oxytocin administration and once following placebo administration, and will complete a series of behavioral tasks (both in and out of the scanner) at both visits.

Timeline

Start

2023-11-01

Primary completion

2024-04-20

Completion

2024-04-20

Outcome

Outcome not reported

Stopped (Business): “COVID made study visits impossible during the funding period.”

Drugs

Indications