drugset / Trial / NCT03869333
Dose Escalating Study of Intramuscular Invaplex[AR-DETOX]
RandomizedSequentialQuadruple-blindPrevention
Summary
The main purpose of this study is to evaluate the safety of a Shigella flexneri 2a detoxified artificial invasin complex (Invaplex\[AR-Detox\]) vaccine candidate administered by intramuscular immunization.
Timeline
- Start
- 2019-03-18
- Primary completion
- 2020-06-12
- Completion
- 2020-06-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | InvaplexAR-Detox | Vaccine | 2.5 ug | Intramuscular |
| Subject | InvaplexAR-Detox | Vaccine | 10 ug | Intramuscular |
| Subject | InvaplexAR-Detox | Vaccine | 25 ug | Intramuscular |