Inhaled NO in IPF and COPD During 6 Minute Walk Test

Phase 2 Unknown 100 enrolled Rabin Medical Center Bellerophon · collab

RandomizedParallel-groupSingle-blindTreatment

Summary

Our objective is to evaluate the influence of inhaled NO on the saturation and exercise capacity of patients with COPD and IPF. each participant will undergo two six minute walk tests, one with inhaled NO and the other with placebo.

Timeline

Start: 2019-03-04
Primary completion: 2020-03-04
Completion: 2020-09-01

Publications

Freidkin L, Kramer MR, Rosengarten D, Izhakian S, Taieb S, Pertzov B. The acute effect of inhaled nitric oxide on the exercise capacity of patients with advanced interstitial lung disease: a randomized controlled trial. BMC Pulm Med. 2024 May 10;24(1):226. doi: 10.1186/s12890-024-03051-4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Nitric Oxide	Other / unclassified	45 ppm	Inhaled
Subject	Nitric Oxide	Other / unclassified	75 ppm	Inhaled
Subject	Nitric Oxide	Other / unclassified	115 ppm	Inhaled

Inhaled NO in IPF and COPD During 6 Minute Walk Test

Summary

Timeline

Publications

Drugs

Indications