drugset / Trial / NCT03877562
The Effect of CORT118335 on Olanzapine-Induced Weight Gain
RandomizedParallel-groupDouble-blindPrevention
Summary
This study will investigate if there is any difference in the amount of weight gained by participants taking olanzapine with CORT118335 compared with olanzapine with placebo (a dummy test medicine which looks like CORT118335 but contains no active medicine). Safety and tolerability of CORT118335 when taken with olanzapine will also be evaluated.
Timeline
- Start
- 2019-04-01
- Primary completion
- 2020-03-13
- Completion
- 2020-03-25
Outcome
Met primary endpoint
release “our selective cortisol modulator miricorilant significantly reduced the weight gain caused by the commonly prescribed antipsychotic medication olanzapine” corcept.com ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Miricorilant | Small molecule | 600 mg | Oral |
| Background | Olanzapine | Small molecule | 10 mg | Oral |