drugset / Trial / NCT03881904

OCP Pretreatment in PCOS Patients Undergoing ICSI Using Antagonist Protocol

NCT03881904

Phase 1/2 Unknown 740 enrolled Ain Shams University
RandomizedParallel-groupOpen-labelTreatment

Summary

373 women with PCOS undergoing a trial of IVF/ICSI will receive OCP from day 2 of the preceding cycle for 21 days followed by GnRH antagonist COH. Another 373 women with PCOS undergoing a trial of IVF/ICSI will start GnRH antagonist COH directly without OCP pretreatment. Both groups will be followed up for effect on ongoing pregnancy rate.

Timeline

Start
2017-06-01
Primary completion
2019-07-01
Completion
2019-07-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Gestodene Small molecule 0.075 mg
Comparator ethinyl estradiol Small molecule 0.03 mg

Indications