drugset / Trial / NCT03882281

Pharmacokinetics Profiles of HQP1351 Under Fasting and High-fat Meals in Patients With Chronic Myeloid Leukemia

NCT03882281

RandomizedCrossoverOpen-labelTreatment

Summary

The purpose of this study is to characterize the pharmacokinetics of HQP1351 in participants with resistant chronic myeloid leukemia (CML) in chronic phase (CP) after high-fat and fasting meals separately(Selection of high-fat meal spectrum:《The Food - Effect Bioavailability and Fed Bioequivalence Studies》high fat diet should be 800-1000 kcal heat.).

Timeline

Start
2019-03-25
Primary completion
2019-11-16
Completion
2019-11-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Olverembatinib Small molecule 30 mg Oral