drugset / Trial / NCT03883386

Loratadine for Improvement of Bone Pain in Patients With Chronic Granulocyte-Colony Stimulating Factor (G-CSF) Use

NCT03883386

Phase 2 Terminated 3 enrolled University of Michigan
RandomizedCrossoverTriple-blindSupportive care

Summary

G-CSF causes a release of histamine that may be a cause of chronic bone pain. Loratadine targets histamine, and so may be effective in reducing bone pain.The researchers plan to prospectively assess the effectiveness of loratadine for chronic bone pain in patients with chronic G-CSF use.

Timeline

Start
2019-06-24
Primary completion
2019-10-18
Completion
2019-10-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Loratadine Small molecule 10 mg

Indications