A Study to Evaluate the Drug-drug Interaction Between Telmisartan, Amlodipine and Hydrochlorothiazide

Phase 1 Completed 30 enrolled IlDong Pharmaceutical Co Ltd

RandomizedCrossoverOpen-labelTreatment

Summary

A randomized, open-label, single dose, 3-way crossover study to evaluate the drug-drugs interaction between Telmisartan, Amlodipine and Hydrochlorothiazide in healthy male volunteers

Timeline

Start: 2013-12-19
Primary completion: 2014-02-19
Completion: 2014-02-19

Publications

Moon SJ, Jeon JY, Yu KS, Kim MG. Pharmacokinetic Interaction Among Telmisartan, Amlodipine, and Hydrochlorothiazide After a Single Oral Administration in Healthy Male Subjects. Clin Ther. 2019 Nov;41(11):2273-2282. doi: 10.1016/j.clinthera.2019.08.020. Epub 2019 Sep 26.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Amlodipine	Other / unclassified	10 mg	Oral
Subject	Hydrochlorothiazide	Unknown	25 mg	Oral
Subject	Telmisartan	Other / unclassified	80 mg	Oral

Indications

No indication recorded.