drugset / Trial / NCT03893617
Brief Stresses Experimental Study
RandomizedParallel-groupTriple-blindBasic science
Summary
The goal of this study is to examine the impact of psychological stress on DNA integrity by conducting an experiment under controlled conditions with healthy volunteers to directly test the extent to which acute stress increases DNA damage, while simultaneously testing the blocking effects of pre-treatment with propranolol, and exploring key hypothesized mediators and moderators of the severity of the DNA damage.
Timeline
- Start
- 2017-10-05
- Primary completion
- 2022-01-27
- Completion
- 2022-01-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propranolol | Small molecule | 80 mg | Oral |