drugset / Trial / NCT03897348
Pilot Human Lab Study of Lacosamide in Alcohol Use Disorder (AUD)
Phase 2
Completed
4 enrolled
University of California, San Francisco
San Francisco VA Health Care System · collab
RandomizedCrossoverTriple-blindTreatment
Summary
The overall goal of the proposed project is to improve the treatment of individuals with AUD. The investigators will conduct the first pilot human laboratory study to assess the effects of two doses of lacosamide on alcohol drinking and craving. The investigators will assess its effects on reducing alcohol intake using a human laboratory method, the Yale Alcohol Drinking Paradigm (ADP). The investigators will also assess the feasibility of the Alcohol Drinking Paradigm (ADP) in order to position our research team to have the capacity to conduct future, larger, hypothesis-testing human laboratory-based experiments designed to test the efficacy of potential alcohol treatments.
Timeline
- Start
- 2018-09-17
- Primary completion
- 2019-06-12
- Completion
- 2019-06-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lacosamide | Other / unclassified | 100 mg | Oral |
| Subject | Lacosamide | Other / unclassified | 200 mg | Oral |