drugset / Trial / NCT03897348

Pilot Human Lab Study of Lacosamide in Alcohol Use Disorder (AUD)

NCT03897348

RandomizedCrossoverTriple-blindTreatment

Summary

The overall goal of the proposed project is to improve the treatment of individuals with AUD. The investigators will conduct the first pilot human laboratory study to assess the effects of two doses of lacosamide on alcohol drinking and craving. The investigators will assess its effects on reducing alcohol intake using a human laboratory method, the Yale Alcohol Drinking Paradigm (ADP). The investigators will also assess the feasibility of the Alcohol Drinking Paradigm (ADP) in order to position our research team to have the capacity to conduct future, larger, hypothesis-testing human laboratory-based experiments designed to test the efficacy of potential alcohol treatments.

Timeline

Start
2018-09-17
Primary completion
2019-06-12
Completion
2019-06-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Lacosamide Other / unclassified 100 mg Oral
Subject Lacosamide Other / unclassified 200 mg Oral