Effect of PRP Injection in Releiving of Symptoms of Senile Vaginitis

Phase 1 Unknown 30 enrolled Ain Shams University Netherlands: Ministry of Health, Welfare and Sports · collab

RandomizedSingle-groupSingle-blindTreatment

Summary

30 postmenopausal females with senile vaginitis will be enrolled with score of \<15 on the Gloria Bachman Vaginal Health Index (VHI) intramucosal injections of PRP will be adminstered and perform clinical evaluations at 0, 1, 3, and 6 months.

Timeline

Start: 2019-03-18
Primary completion: 2019-09-30
Completion: 2019-10-30

Outcome

Met primary endpoint

paper After four months of treatment, the FSFI scores significantly improved in the PRP group (19.0 ± 4.5 vs. 9.7 ± 4.3, P < 0.001). PMID 41291715 ↗

Publications

Hamid ASA, AbdAllah AM, Fathi HM, Eldin AMB, Abd El Hadi RMM. Value of injection of plasma-rich platelets in the vaginal mucosa in cases with vulvovaginal atrophy: a prospective double-blinded randomized controlled study. BMC Womens Health. 2025 Nov 25;25(1):576. doi: 10.1186/s12905-025-04076-5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Platelet Rich Plasma	Other / unclassified	5 ml	Other