drugset / Trial / NCT03910387
Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic Cancer
Phase 2
Completed
23 enrolled
Emory University
Lexicon Pharmaceuticals · collabNational Cancer Institute (NCI) · collab
RandomizedParallel-groupOpen-labelSupportive care
Summary
This phase II trial studies how well telotristat ethyl works in promoting weight stability in patients with pancreatic adenocarcinoma that has come back and spread to other places in the body. Telotristat ethyl may decrease bowel movements which may make patients gain weight. Stabilizing weight may help patients tolerate chemotherapy better and improve longevity.
Timeline
- Start
- 2019-04-17
- Primary completion
- 2022-06-29
- Completion
- 2022-06-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Telotristat Ethyl | Unknown | — | Oral |
| Background | Gemcitabine | Small molecule | — | — |
| Background | Paclitaxel | Small molecule | — | — |