drugset / Trial / NCT03913455
Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung Cancer
Phase 2
Completed
24 enrolled
Shadia Jalal, MD
Astex Pharmaceuticals, Inc. · collabIndiana University · collab
NaSingle-groupOpen-labelTreatment
Summary
This is a phase II, open-label, single arm, single-stage study. Both, chemo-sensitive and chemo-resistant patients will be enrolled and treated with 4 cycles of combination of Guadecitabine and carboplatin
Timeline
- Start
- 2019-06-06
- Primary completion
- 2021-04-14
- Completion
- 2022-02-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carboplatin | Small molecule | — | — |
| Subject | Guadecitabine | Oligonucleotide (other) | 30 mg/m2 | Subcutaneous |