drugset / Trial / NCT03922204

A Study of Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies

NCT03922204 ↗

Phase 1 Completed 72 enrolled Merus B.V.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is an open-label, non-randomized, Phase 1 study to determine the safety, tolerability, and preliminary efficacy of MCLA-145 in adult patients with advanced metastatic solid tumors or B-cell lymphomas. The study will be conducted in 2 parts.

Timeline

Start
2019-05-08
Primary completion
2024-11-07
Completion
2024-11-07

Drugs

EvaluationDrugModalityDoseRoute
Subject MCLA-145 Monoclonal antibody — Intravenous
Subject Pembrolizumab Monoclonal antibody 200 mg —