drugset / Trial / NCT03923140

A Clinical Study of Tranilast in the Treatment of Cryopyrin-Associated Periodic Syndrome (CAPS)

NCT03923140

Phase 2 Unknown 71 enrolled Peking Union Medical College Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective cohort study to observe the efficacy and safety of tranilast in CAPS patients. The investigators would analyze the changes in Auto-Inflammatory Diseases Activity Index (AIDAI) before and after treatment as well as changes in inflammatory markers, patients' and physician's global assessment of disease activity to determine the efficacy and safety of tranilast.

Timeline

Start
2019-05-23
Primary completion
2024-04
Completion
2024-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Tranilast Small molecule 5 mg/kg
Subject Tranilast Small molecule 0.1 g