drugset / Trial / NCT03925974

KN026 in Patients With HER2 Expressing Gastric/Gastroesophageal Junction Cancer

NCT03925974

Phase 2 Completed 45 enrolled Jiangsu Alphamab Biopharmaceuticals Co., Ltd
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is an open-label, phase 2 study of KN026 in subjects with HER2 expressing gastric/gastroesophageal junction cancer to evaluate efficacy and safety. The subjects will receive KN026 10 mg/kg QW or 20 mg/kg Q2W or 30mg/kg Q3W until progressive disease, unacceptable toxicity or death.

Timeline

Start
2019-06-17
Primary completion
2022-05-31
Completion
2022-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject KN026 Monoclonal antibody 10 mg/kg
Subject KN026 Monoclonal antibody 20 mg/kg
Subject KN026 Monoclonal antibody 30 mg/kg