drugset / Trial / NCT03926000

Pregabalin Premedication for Knee Arthroscopy

NCT03926000

Unknown 112 enrolled Menoufia University
RandomizedCrossoverQuadruple-blindOther

Summary

Outpatient arthroscopic knee surgery can be performed with general or regional anesthesia. Recent data suggest that spinal and epidural anesthesia require longer discharge times than the newer shorter-acting general anesthetic drugs. Ideal premedication drug should relieve anxiety, produce amnesia and sedation, decrease secretions, prevent nausea and vomiting, have dose sparing effect on the anaesthetic drugs, and suppress pressor response to laryngoscopy and intubation. Recently, gabapentin and pregabalin were suggested as pre-operative drugs to decrease anxiety, stress response to laryngoscopy and post operative pain.

Timeline

Start
2019-06
Primary completion
2019-11
Completion
2019-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pregabalin Small molecule 150 mg

Indications

No indication recorded.