Safety and Immunogenicity of Typhax, a Typhoid Vaccine

Summary

This was a randomized, double-blind, ascending dose study conducted at a single clinical research center.

Timeline

Start

2016-03-28

Primary completion

2017-02-15

Completion

2017-02-15

Publications

• Cartee RT, Thanawastien A, Griffin Iv TJ, Mekalanos JJ, Bart S, Killeen KP. A phase 1 randomized safety, reactogenicity, and immunogenicity study of Typhax: A novel protein capsular matrix vaccine candidate for the prevention of typhoid fever. PLoS Negl Trop Dis. 2020 Jan 6;14(1):e0007912. doi: 10.1371/journal.pntd.0007912. eCollection 2020 Jan.

Drugs

Indications