drugset / Trial / NCT03931668
Tolerance, PK and PD Effects Study of TPN-672 in Chinese Healthy Volunteers
Phase 0
Unknown
62 enrolled
Shanghai Mental Health Center
Jiangsu Kanion Pharmaceutical Co., Ltd · collab
RandomizedSequentialDouble-blindOther
Summary
This is a single-site, randomized, double-blind, placebo-controlled, incremental phase I clinical trial to evaluate preliminarily the tolerance, pharmacokinetics and pharmacodynamic effects of TPN672 maleate in Chinese healthy volunteers after single dose administration.
Timeline
- Start
- 2019-04-17
- Primary completion
- 2020-10-17
- Completion
- 2020-12-17
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | TPN-672 | Unknown | 0.125 mg | — |
| Subject | TPN-672 | Unknown | 0.25 mg | — |
| Subject | TPN-672 | Unknown | 0.5 mg | — |
| Subject | TPN-672 | Unknown | 1 mg | — |
| Subject | TPN-672 | Unknown | 2 mg | — |
| Subject | TPN-672 | Unknown | 3 mg | — |
| Subject | TPN-672 | Unknown | 4 mg | — |