drugset / Trial / NCT03934450
Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose Regimen
Non-randomizedCrossoverSingle-blindBasic science
Summary
To investigate the comparative tolerability, metabolism and pharmacokinetics of individual enantiomers of PQ in healthy human volunteers, receiving study drug over the course of 7 days.
Timeline
- Start
- 2018-08-17
- Primary completion
- 2019-05-01
- Completion
- 2019-05-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Primaquine | Small molecule | 30 mg | — |
| Comparator | Primaquine | Small molecule | 45 mg | — |
| Subject | RPQ | Unknown | 15 mg | — |
| Subject | RPQ | Unknown | 22.5 mg | — |
| Comparator | SPQ | Unknown | 15 mg | — |
| Comparator | SPQ | Unknown | 22.5 mg | — |