drugset / Trial / NCT03936465
Study of the Bromodomain (BRD) and Extra-Terminal Domain (BET) Inhibitors BMS-986158 and BMS-986378 in Pediatric Cancer
Non-randomizedParallel-groupOpen-labelTreatment
Summary
Arm 1 of this research study is studying an investigational drug called BMS-986158 as a possible treatment for pediatric solid tumors or lymphoma. Arm 2 of this research study is studying an investigational drug called BMS-986378 (also known as CC-90010) as a possible treatment for pediatric brain tumors or pediatric tumors that have spread to the brain.
Timeline
- Start
- 2019-09-27
- Primary completion
- 2024-03-16
- Completion
- 2024-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | EZOBRESIB | Small molecule | — | Oral |
| Subject | Trotabresib | Small molecule | — | Oral |