drugset / Trial / NCT03937609
TITRATE (inducTIon for acuTe ulceRATivE Colitis)
RandomizedParallel-groupOpen-labelTreatment
Summary
The aim of this study is to investigate whether intensive, personalized IFX dosing by using a pharmacokinetics driven dashboard system during the induction phase in patients with acute severe UC leads to increased treatment success (as defined by clinical and endoscopic response at week 6) as compared to the standard dosing.
Timeline
- Start
- 2019-09-04
- Primary completion
- 2024-12-15
- Completion
- 2024-12-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Infliximab | Monoclonal antibody | 5 mg/kg | Intravenous |