drugset / Trial / NCT03944239

Safety and Efficacy of Subretinal Transplantation of Clinical Human Embryonic Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Retinitis Pigmentosa

NCT03944239 ↗

Phase 1 Active not recruiting 25 enrolled Qi Zhou Beijing Tongren Hospital · collab
NaSingle-groupOpen-labelOther

Summary

This project intends to transplant a clinical level human embryonic stem cells derived retinal pigment epithelium into subretinal space to treat eetinitis pigmentosa(RP) diseases. Through the statistical analysis EDTRS, BCVA, OCT, ERG, Fluorescein angiography, Ophthalmic AB ultrasound changes between before and after the treatment to assess the efficacy and safety 0f RPE transplants to treat RP disease.

Timeline

Start
2021-05-19
Primary completion
2026-12-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Retinal pigment epitheliums Cell therapy 150000 cells Other

Indications