drugset / Trial / NCT03957720
The Individual Therapy for Patients With Wilson's Disease
Non-randomizedSequentialSingle-blindTreatment
Summary
Based on the genotype characteristics and genotype-phenotype-treatment prognosis data of Chinese WD patients, this study intends to further optimize the treatment regimen of Chinese WD patients and formulate individualized treatment regimens for each genotype, so as to further improve the prognosis of patients.
Timeline
- Start
- 2019-03-15
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | 2,3-dimercapto-1-propanesulfonic acid | Small molecule | 500 mg | — |
| Subject | 2,3-dimercapto-1-propanesulfonic acid | Small molecule | 1000 mg | — |
| Subject | Succimer | Small molecule | 35 mg/kg | — |
| Subject | Succimer | Small molecule | 750 mg | — |
| Subject | Succimer | Small molecule | 1000 mg | — |
| Subject | Zinc gluconate | Small molecule | 140 mg | — |
| Subject | Zinc gluconate | Small molecule | 210 mg | — |
| Subject | penicillamine | Unknown | 250 mg | — |
| Subject | penicillamine | Unknown | 1500 mg | — |