drugset / Trial / NCT03960788

Gadoxetate Sodium Enhanced MRI as a Biomarker for Aggressive Prostate Cancer

NCT03960788

Phase 0 Unknown 50 enrolled University of Cincinnati
NaSingle-groupOpen-labelDiagnostic

Summary

The purpose of this research study is to test to see if Gadoxetate Sodium is a useful contrast agent for detecting prostate cancer during magnetic resonance imaging (MRI). Gadoxetate Sodium is an FDA approved contrast agent that is currently used to detect liver cancer. Gadoxetate Sodium shows promise in identifying more aggressive prostate cancers at earlier stages. The study will also test to see if specific genes are expressed in the left over tissue samples from previous prostate fusion biopsy. The investigators hypothesize that Gadoxetate Sodium-enhanced MRI can differentiate aggressive prostate cancer and predict its early recurrence.

Timeline

Start
2018-01-02
Primary completion
2020-01-02
Completion
2021-01-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Gadoxetate Disodium Diagnostic / imaging agent 0.1 ml