drugset / Trial / NCT03961100
A Performance and Bioavailability Study of Entrectinib in Healthy Volunteers.
RandomizedCrossoverOpen-labelTreatment
Summary
This study will evaluate the bioavailability, palatability, safety and tolerability of entrectinib in healthy volunteers. Part 1 of the study will explore the performance of entrectinib multi-particle formulation. Part 2 will evaluate the effect of drug substance particle size on entrectinib bioavailability.
Timeline
- Start
- 2019-06-06
- Primary completion
- 2019-08-09
- Completion
- 2019-08-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Entrectinib | Small molecule | 200 mg | Oral |
| Subject | Entrectinib | Small molecule | 600 mg | Oral |