Lactobacillus Johnsonii in Children and Adolescents With T1D

Summary

While genetics demonstrated a major risk factor for the development of type 1 diabetes (T1D), microbiota dysbiosis has been suggested as an elicitor in immunological tolerance and of beta cell autoimmunity. The probiotic Lactobacillus johnsonii N6.2 may prevent or restore the gut flora and show systemic impacts and adaptive immunity in the T1D population thereby preserving beta cell function.

Timeline

Start

2019-10-10

Primary completion

2026-01-23

Completion

2026-01-23

Drugs

Indications