drugset / Trial / NCT03965728
Study to Investigate Safety, Tolerability, Pharmacokinetics, and Drug-drug Interaction of Multiple Oral Doses of BAY1830839 in Healthy Male Participants
RandomizedSequentialDouble-blindBasic science
Summary
The aim of this study is to investigate safety, tolerability and pharmacokinetics of increasing repeated oral doses of BAY1830839 in healthy male participants including the investigation of any potential drug-drug interactions of BAY1830839 with midazolam and methotrexate. In addition, the effects of BAY180839 on exploratory pharmacodynamics biomarkers in healthy participants will be investigated.
Timeline
- Start
- 2019-06-05
- Primary completion
- 2022-01-21
- Completion
- 2022-05-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BAY1830839 | Unknown | — | Oral |
| Subject | Methotrexate | Small molecule | — | Oral |
| Subject | Midazolam | Small molecule | — | Oral |
Indications
No indication recorded.