drugset / Trial / NCT03974217

Talazoparib for Cohesin-Mutated AML and MDS With Excess Blasts

NCT03974217

Phase 1 Active not recruiting 13 enrolled Dana-Farber Cancer Institute Pfizer · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This research study is testing if Talazoparib is an effective treatment for patients with AML and MDS that have a mutation in the cohesin complex.

Timeline

Start
2019-08-01
Primary completion
2025-04-03
Completion
2027-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Decitabine Small molecule
Subject Talazoparib Small molecule Oral

Indications