Ramipril, Endothelial Function and Endothelial Progenitor Cells in Patients With Systemic Lupus Erythematosus

Phase 2/3 Completed 37 enrolled Federal University of São Paulo Fundação de Amparo à Pesquisa do Estado de São Paulo · collab

RandomizedParallel-groupSingle-blindPrevention

Summary

The aim of this study was to evaluate the effect of ramipril on the endothelial function and on the number of endothelial progenitor cells (EPCs) in systemic lupus erythematosus (SLE) patients.

Timeline

Start: 2011-03
Primary completion: 2013-08
Completion: 2013-09

Publications

Oliveira ACD, Arismendi MI, Machado LSG, Sato EI. Ramipril Improves Endothelial Function and Increases the Number of Endothelial Progenitor Cells in Patients With Systemic Lupus Erythematosus. J Clin Rheumatol. 2022 Oct 1;28(7):349-353. doi: 10.1097/RHU.0000000000001869. Epub 2022 Jun 8.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ramipril	Small molecule	10 mg	—

Ramipril, Endothelial Function and Endothelial Progenitor Cells in Patients With Systemic Lupus Erythematosus

Summary

Timeline

Publications

Drugs

Indications