Effects of Different Omeprazole Dosing on Gastric pH in Non-variceal Upper Gastrointestinal Bleeding

Phase 4 Completed 50 enrolled Medical University of Bialystok National Science Centre, Poland · collab

RandomizedParallel-groupSingle-blindTreatment

Summary

The aim of the study is to identify the best method of omeprazole (OME) application with respect to intragastric pH, cytochrome P450 2C19 (CYP2C19) genotype and phenotype.

Timeline

Start: 2010-09-09
Primary completion: 2013-06-08
Completion: 2013-06-08

Publications

Results Chwiesko A, Charkiewicz R, Niklinski J, Luczaj W, Skrzydlewska E, Milewski R, Baniukiewicz A, Wroblewski E, Rosolowski M, Dabrowski A. Effects of different omeprazole dosing on gastric pH in non-variceal upper gastrointestinal bleeding: A randomized prospective study. J Dig Dis. 2016 Sep;17(9):588-599. doi: 10.1111/1751-2980.12393.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Omeprazole	Other / unclassified	8 mg	Intravenous
Comparator	Omeprazole	Other / unclassified	40 mg	Intravenous

Indications

No indication recorded.